Zheng Hu

Latest

Clonal expansion dictates the efficacy of mitochondrial lineage tracing in single cells
Single-cell phylodynamic inference of tissue development and tumor evolution with scPhyloX
Immune-tumor interaction dictates spatially directed evolution of esophageal squamous cell carcinoma
Tumor phylogeography reveals block-shaped spatial heterogeneity and the mode of evolution in Hepatocellular Carcinoma
PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes
A genetic bottleneck of mitochondrial DNA during human lymphocyte development
Delineating the longitudinal tumor evolution using organoid models
Looking backward in time to define the chronology of metastasis
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases
Quantitative evidence for early metastatic seeding in colorectal cancer
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Genetic Load and Potential Mutational Meltdown in Cancer Cell Populations
Is the evolution in tumors Darwinian or non-Darwinian?
Big Bang tumor growth and clonal evolution
Between-region genetic divergence reflects the mode and tempo of tumor evolution
A population genetics perspective on the determinants of intra-tumor heterogeneity
Inferring tumor phylogenies from multi-region sequencing
Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution
Age-dependent transition from cell-level to population-level control in murine intestinal homeostasis revealed by coalescence analysis